Orforglipron · Once-Daily Tablet

New — MHRA approved August 2026

Foundayo

Foundayo (orforglipron) is a once-daily weight management tablet and the first non-peptide GLP-1 medicine licensed in the UK. Unlike other oral GLP-1 treatments, it is stable in stomach acid — so there are no fasting rules, no waiting period, and no restrictions on when you take it.

Take it any time of day — with or without food

Once-daily tablet — no needles

No fasting or waiting period before you eat or drink

Six dose strengths — increased gradually under supervision

Clinician-supervised treatment with ongoing support

MHRA Approved

UK Prescribers

No Food Restrictions

Starting From £99 /month

Includes medication, consultations & support · 30-day supply

Start Journey →

No needles · Tracked, discreet delivery · Cancel anytime

What Makes Foundayo Different

A tablet that fits around your day

Most oral GLP-1 medicines have to be taken on an empty stomach, with a strict waiting period before food. Foundayo does not.

No fasting rules

Take it with or without food, at whatever time of day suits you. There is no waiting period before eating or drinking.

Stable in stomach acid

Foundayo is a non-peptide GLP-1 — the first licensed in the UK. Its structure means it does not need the protective dosing routine other oral GLP-1s require.

Simple daily routine

One tablet, swallowed whole. No injections, no pens, no sharps disposal, nothing to refrigerate.

Gradual & Personalised

How Foundayo Dosing Works

Six dose strengths, with a minimum of 30 days at each before any increase. Most patients reach their maintenance dose after three to four months.

1

0.8mg Starting Dose

£99 · 30 days

At least 30 days while your body adjusts to the medication.

2

2.5mg Step 2

£119 · 30 days

First increase — appetite changes typically begin around here.

3

5.5mg Step 3

£129 · 30 days

A further increase if you are tolerating treatment well.

4

9mg Step 4

£159 · 30 days

Many patients find their maintenance dose at this level.

5

14.5mg Step 5

£189 · 30 days

A higher dose for patients who need additional support.

6

17.2mg Maximum Dose

£199 · 30 days

The highest licensed strength. Not everyone needs to reach it.

Important: Personalised Dosing — You can stay on a strength for longer if side effects need more time to settle, or if you are already losing weight steadily. Your prescriber decides each increase with you, and can adjust it at any reorder.

Foundayo FAQs

Both are once-daily tablets, but they contain different medicines and are taken differently. Wegovy tablets contain semaglutide and must be taken on an empty stomach, with at least 30 minutes before food, drink or other medicines. Foundayo contains orforglipron, which is stable in stomach acid — so you can take it at any time of day, with or without food.

One tablet, once a day, swallowed whole with water. Do not crush, split or chew it. You can take it at whatever time of day suits you, with or without food.

Foundayo (orforglipron) is a GLP-1 receptor agonist. It reduces appetite, slows digestion and helps regulate blood sugar, so you feel satisfied with less food. It is the first non-peptide GLP-1 medicine to be licensed for weight management in the UK.

Yes. Use the screening form and tell us your current treatment and dose. Your prescriber will review it with you and confirm the appropriate Foundayo starting strength — switching does not always mean starting at the lowest dose.

The most common side effects are mild nausea, reduced appetite and digestive discomfort, particularly in the first weeks and after each dose increase. These usually settle. The gradual titration across six strengths, with at least 30 days at each, is designed to keep side effects manageable.

Foundayo is generally suitable for adults with a BMI of 30 or above, or 27 or above alongside a weight-related health condition. Complete the screening assessment and one of our UK-registered prescribers will confirm whether it is appropriate for you.